Scheidig, Axel J.: search on Z-Library

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1

Human mitochondrial amidoxime reducing component (mARC): An electrochemical method for identifying new substrates and inhibitors

Kalimuthu, Palraj, Havemeyer, Antje, Clement, Bernd, Kubitza, Christian, Scheidig, Axel J., Bernhardt, Paul V.

Journal:

Electrochemistry Communications

Year:

2017

Language:

english

File:

PDF, 383 KB

english, 2017

2

Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases

Altmeyer, Markus, Amtmann, Eberhard, Heyl, Carina, Marschner, Aline, Scheidig, Axel J., Klein, Christian D.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 2.62 MB

english, 2014

3

Chemoenzymatische Synthese fluoreszierender Rab-7-Proteine: Werkzeuge zum Studium des vesikulären Transports in Zellen

David J. Owen, Kirill Alexandrov, Elena Rostkova, Axel J. Scheidig, Roger S. Goody, Herbert Waldmann

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 109 KB

german, 1999

4

Chemo-Enzymatic Synthesis of Fluorescent Rab 7 Proteins: Tools to Study Vesicular Trafficking in Cells

David J. Owen, Kirill Alexandrov, Elena Rostkova, Axel J. Scheidig, Roger S. Goody, Herbert Waldmann

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

5

Comprehensive Structural Characterization of the Bacterial Homospermidine Synthase–an Essential Enzyme of the Polyamine Metabolism

Krossa, Sebastian, Faust, Annette, Ober, Dietrich, Scheidig, Axel J.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.89 MB

english, 2016

6

Structure-Function Relationships of Antimicrobial Peptides and Proteins with Respect to Contact Molecules on Pathogen Surfaces

Zhang, Ruiyan, Eckert, Thomas, Lutteke, Thomas, Hanstein, Stefan, Scheidig, Axel, M. J. J. Bonvin, Alexandre, E. Nifantiev, Nikolay, Kozar, Tibor, Schauer, Roland, Abdulaziz Enani, Mushira, Siebert, H

Journal:

Current Topics in Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 752 KB

english, 2015

7

Structural and functional comparison of the non-structural protein 4B in flaviviridae

Christoph Welsch, Mario Albrecht, Jochen Maydt, Eva Herrmann, Martin Walter Welker, Christoph Sarrazin, Axel Scheidig, Thomas Lengauer, Stefan Zeuzem

Journal:

Journal of Molecular Graphics and Modelling

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

8

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of alzheimer's amyloid β-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specificities

Axel J. Scheidig, Thomas R. Hynes, Laura A. Pelletier, James A. Wells, Anthony A. Kossiakoff

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 11.82 MB

english, 1997

9

2′Halo-ATP and -GTP analogues: Rational phasing tools for protein crystallography

Mathias Gruen, Christian Becker, Andrea Beste, Jochen Reinstein, Axel J. Scheidig, Roger S. Goody

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 161 KB

english, 1999

10

The Crystal Structure of Human PAPS Synthetase 1 Reveals Asymmetry in Substrate Binding

Stefan Harjes, Peter Bayer, Axel J. Scheidig

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 1.11 MB

english, 2005

11

Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes

Kubitza, Christian, Bittner, Florian, Ginsel, Carsten, Havemeyer, Antje, Clement, Bernd, Scheidig, Axel J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

12

Drug Metabolism by the Mitochondrial Amidoxime Reducing Component (mARC): Rapid Assay and Identification of New Substrates

Indorf, Patrick, Kubitza, Christian, Scheidig, Axel J., Kunze, Thomas, Clement, Bernd

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 434 KB

2019

13

Time-Resolved Macromolecular Crystallography || Time-Resolved Crystallography on H-ras p21 [and Discussion]

Axel J. Scheidig, Emil F. Pai, Ilme Schlichting, John Corrie, Gordon P. Reid, Alfred Wittinghofer, Roger S. Goody, A. Liljas and K. Moffat

Journal:

Philosophical Transactions of the Royal Society Physical and Engineering Sciences (1990-1995)

Year:

1992

Language:

english

File:

PDF, 1.63 MB

english, 1992

14

Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans

Kisiela, Michael, Faust, Annette, Ebert, Bettina, Maser, Edmund, Scheidig, Axel J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.73 MB

english, 2017

15

X-ray Crystal Structure Analysis of the Catalytic Domain of the Oncogene Product p21H-rasComplexed with Caged GTP and Mant dGppNHp

Axel J. Scheidig, Sybille M. Franken, John E.T. Corrie, Gordon P. Reid, Alfred Wittinghofer, Emil F. Pai, Roger S. Goody

Journal:

Journal of Molecular Biology

Year:

1995

Language:

english

File:

PDF, 1.22 MB

english, 1995

16

Sulfate Acts as Phosphate Analog on the Monomeric Catalytic Fragment of the CPx-ATPase CopB from Sulfolobus solfataricus

Mathias Lübben, Jörn Güldenhaupt, Martin Zoltner, Katrin Deigweiher, Peter Haebel, Claus Urbanke, Axel J. Scheidig

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

17

Characterization of the ternary complex between Rab7, REP-1 and Rab geranylgeranyl transferase

Kirill Alexandrov, Iris Simon, Vyacheslav Yurchenko, Andrei Iakovenko, Elena Rostkova, Axel J. Scheidig, Roger S. Goody

Journal:

Year:

1999

Language:

english

File:

PDF, 747 KB

english, 1999

18

The sulfur-oxidizing enzyme system of paracoccus pantotrophus: proteins and reaction

Cornelius G. Friedrich, Armin Quentmeier, Frank Bardischewsky, Dagmar Rother, Petra Hellwig, Wolfgang Lubitz, Tresfore Dambe, Axel Scheidig

Journal:

Journal of Inorganic Biochemistry

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

19

Molecular basis of transmembrane signalling by sensory rhodopsin II–transducer complex

Gordeliy, Valentin I., Labahn, Jörg, Moukhametzianov, Rouslan, Efremov, Rouslan, Granzin, Joachim, Schlesinger, Ramona, Büldt, Georg, Savopol, Tudor, Scheidig, Axel J., Klare, Johann P.

Journal:

Year:

2002

Language:

english

File:

PDF, 354 KB

english, 2002

20

Synthesis of 2′-Iodo- and 2′-Bromo-ATP and GTP Analogues as Potential Phasing Tools for X-ray Crystallography

Gruen, Mathias, Becker, Christian, Beste, Andrea, Siethoff, Christoph, Scheidig, Axel J., Goody, Roger S.

Journal:

Nucleosides and Nucleotides

Year:

1999

Language:

english

File:

PDF, 667 KB

english, 1999

21

Crystal structure of pyrrolizidine alkaloid N -oxygenase from the grasshopper Zonocerus variegatus

Kubitza, Christian, Faust, Annette, Gutt, Miriam, Gäth, Luzia, Ober, Dietrich, Scheidig, Axel J.

Journal:

Acta Crystallographica Section D Structural Biology

Year:

2018

Language:

english

File:

PDF, 2.49 MB

english, 2018

22

A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction

Klink, Björn U., Goody, Roger S., Scheidig, Axel J.

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 611 KB

english, 2006

23

Crystal Structure of NADP(H)-Dependent 1,5-Anhydro- d -fructose Reductase from Sinorhizobium morelense at 2.2 Å Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis †,‡

Dambe, Tresfore R., Kühn, Annette M., Brossette, Tatjana, Giffhorn, Friedrich, Scheidig, Axel J.

Journal:

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

24

SPIE Proceedings [SPIE SPIE's 1995 International Symposium on Optical Science, Engineering, and Instrumentation - San Diego, CA (Sunday 9 July 1995)] Time-Resolved Electron and X-Ray Diffraction - Time-resolved crystallography on p21H-ras

Scheidig, Axel J., Rentzepis, Peter M.

Year:

1995

Language:

english

File:

PDF, 1.30 MB

english, 1995

25

T4 lysozyme-facilitated crystallization of the human molybdenum cofactor-dependent enzyme mARC

Kubitza, Christian, Ginsel, Carsten, Bittner, Florian, Havemeyer, Antje, Clement, Bernd, Scheidig, Axel J.

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2018

Language:

english

File:

PDF, 884 KB

english, 2018

26

The pre-hydrolysis state of p21ras in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins

Axel J Scheidig, Christoph Burmester, Roger S Goody

Journal:

Year:

1999

Language:

english

File:

PDF, 1.47 MB

english, 1999

27

Interface Analysis of the Complex between ERK2 and PTP-SL

Balasu, Mihaela C., Spiridon, Laurentiu N., Miron, Simona, Craescu, Constantin T., Scheidig, Axel J., Petrescu, Andrei-Jose, Szedlacsek, Stefan E., Nigou, Jérome

Journal:

Year:

2009

Language:

english

File:

PDF, 594 KB

english, 2009

28

High-resolution crystal structure of S. cerevisiae Ypt51(ΔC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis

Heike Esters, Kirill Alexandrov, Alexandru-Tudor Constantinescu, Roger S Goody, Axel J Scheidig

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 678 KB

english, 2000

29

Quantitative Labeling of Long Plasmid DNA with Nanometer Precision

Goran Pljevaljčić, Falk Schmidt, Axel J. Scheidig, Rudi Lurz, Elmar Weinhold

Journal:

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

30

The Unusual Binding Mode of Cnicin to the Antibacterial Target Enzyme MurA Revealed by X-ray Crystallography †

Steinbach, Anke, Scheidig, Axel J., Klein, Christian D.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 842 KB

english, 2008

31

[Methods in Enzymology] Caged Compounds Volume 291 || [14] Use of caged nucleotides to characterize unstable intermediates by x-ray crystallography

Scheidig, Axel J.

Year:

1998

Language:

english

File:

PDF, 875 KB

english, 1998

32

The Involvement of the Mitochondrial Amidoxime Reducing Component (mARC) in the Reductive Metabolism of Hydroxamic Acids

Ginsel, Carsten, Plitzko, Birte, Froriep, Danilo, Stolfa, Diana A., Jung, Manfred, Kubitza, Christian, Scheidig, Axel J., Havemeyer, Antje, Clement, Bernd

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 656 KB

english, 2018

33

10.1038/84104

Goedecke, Karsten, Pignot, Marc, Goody, Roger S., Scheidig, Axel J., Weinhold, Elmar

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 1.27 MB

english, 2001

34

Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for map kinase regulation

Stefan E Szedlacsek, Alexandru R Aricescu, Tudor A Fulga, Louis Renault, Axel J Scheidig

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 593 KB

english, 2001

35

Phosphoisoprenoid Binding Specificity of Geranylgeranyltransferase Type II

Thomä, Nicolas H., Iakovenko, Andrei, Owen, David, Scheidig, Axel S., Waldmann, Herbert, Goody, Roger S., Alexandrov, Kirill

Journal:

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

36

Impact of chemokines on the properties of spinal cord-derived neural progenitor cells in a rat spinal cord lesion model

Knerlich-Lukoschus, Friederike, Krossa, Sebastian, Krause, Jörg, Mehdorn, H. Maximilian, Scheidig, Axel, Held-Feindt, Janka

Journal:

Journal of Neuroscience Research

Year:

2015

Language:

english

File:

PDF, 409 KB

english, 2015

37

Rab-Subfamily-Specific Regions of Ypt7p Are Structurally Different from Other RabGTPases

Alexandru-Tudor Constantinescu, Alexey Rak, Kirill Alexandrov, Heike Esters, Roger S. Goody, Axel J. Scheidig

Journal:

Year:

2002

Language:

english

File:

PDF, 602 KB

english, 2002

38

2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence

Lenz, Thomas, Bonnist, Eleanor Y. M., Pljevaljčić, Goran, Neely, Robert K., Dryden, David T. F., Scheidig, Axel J., Jones, Anita C., Weinhold, Elmar

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 2.18 MB

english, 2007

39

GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivation

Schäfer, Miriam, Granato, Daniela C., Krossa, Sebastian, Bartels, Anne-Kathrin, Yokoo, Sami, Düsterhöft, Stefan, Koudelka, Tomas, Scheidig, Axel J., Tholey, Andreas, Paes Leme, Adriana F., Grötzinger,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

40

Generation of Highly Productive Chinese Hamster Ovary Cells by Application of Metabolic Pool Selection During Cell Line Development

Thiele, Michael, Arnold, Norbert, Scheidig, Axel J., Winkler, Karsten

Journal:

Current Biotechnology

Year:

2019

File:

PDF, 1.36 MB

2019

41

Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras

Franken, Sybille M., Scheidig, Axel J., Krengel, Ute, Rensland, Hans, Lautwein, Alfred, Geyer, Matthias, Scheffzek, Klaus, Goody, Roger S., Kalbitzer, Hans Robert

Journal:

Year:

1993

Language:

english

File:

PDF, 1.77 MB

english, 1993

42

New insight into the dynamic properties and the active site architecture of H-Ras p21 revealed by X-ray crystallography at very high resolution

Björn U Klink, Axel J Scheidig

Journal:

BMC Structural Biology

Year:

2010

Language:

english

File:

PDF, 2.85 MB

english, 2010

43

High resolution crystal structures of human Rab4a in its active and inactive conformations

Silke K. Huber, Axel J. Scheidig

Journal:

Year:

2005

Language:

english

File:

PDF, 838 KB

english, 2005

44

Structure of the cytochrome complex SoxXA of Paracoccus pantotrophus, a heme enzyme initiating chemotrophic sulfur oxidation

Tresfore Dambe, Armin Quentmeier, Dagmar Rother, Cornelius Friedrich, Axel J. Scheidig

Journal:

Journal of Structural Biology

Year:

2005

Language:

english

File:

PDF, 437 KB

english, 2005

45

The structure of substrate-free 1,5-anhydro- D -fructose reductase from Sinorhizobium meliloti 1021 reveals an open enzyme conformation

Schu, Mario, Faust, Annette, Stosik, Beata, Kohring, Gert-Wieland, Giffhorn, Friedrich, Scheidig, Axel J.

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

46

Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins

Heike Esters, Kirill Alexandrov, Andrei Iakovenko, Tania Ivanova, Nicolas Thomä, Vladimir Rybin, Marino Zerial, Axel J Scheidig, Roger S Goody

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 292 KB

english, 2001

47

Moderate discrimination of REP-1 between Rab7⋅GDP and Rab7⋅GTP arises from a difference of an order of magnitude in dissociation rates

Kirill Alexandrov, Iris Simon, Andrei Iakovenko, Birgit Holz, Roger S Goody, Axel J Scheidig

Journal:

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

48

Nucleoside Triphosphatases in Energy Transduction, Cellular Regulation and Information Transfer in Biological Systems || Studies on the Structure and Mechanism of H-ras p21 [and Discussion]

Roger S. Goody, Emil F. Pai, I. Schlichting, Hans Rensland, Axel Scheidig, Sybille Franken, Alfred Wittinghofer, T. J. Mitchison, K. A. Johnson, R. Skinner, D. M. Blow and C. Cremo

Journal:

Philosophical Transactions Biological Sciences

Year:

1992

Language:

english

File:

PDF, 1.78 MB

english, 1992

49

CHO starter cell lines for manufacturing of proteins with pre-defined glycoprofiles

Winkler, Karsten, Thiele, Michael, Berthold, Rita, Kirschenbaum, Nicole, Sczepanski, Marco, Horsten, Henning, Seitz, Susanne, Arnold, Norbert, Scheidig, Axel J, Sandig, Volker

Journal:

BMC Proceedings

Year:

2013

Language:

english

File:

PDF, 134 KB

english, 2013

50

Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17

Krossa, Sebastian, Scheidig, Axel J., Grötzinger, Joachim, Lorenzen, Inken

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.63 MB

english, 2018

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